Medication that inhibit CYP2D6 action, which include paroxetine and quinidine, may possibly bring about lowered clearance of oxycodone which could lead to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Just like all opioid preparations, oxy